Originally Posted by: john of MT

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During these days of more frequent hand washing I've started the routine of hitting the calluses with a good dose of 91% isopropyl alcohol a couple times throughout the day and at bedtime. .....

YMMV.

I also use isopropyl alcohol (Isocol) to help dry out the skin. It can help with soreness as well. I've also started wearing a rubber glove on my "fret" hand when washing the dishes, If I think of it I use some moisterising cream before going to bed.