As I have previously posted, I purchased a Squier to save wear on my Gibson, and I just love playing the guitar. Extremely comfortable neck, great action (I got really lucky on this deal), and I love that single coil sound when I am in the mood. However, Fender could not have designed a guitar with the knobs more in the fricken way! I will be modding it to a single master tone so I can move that offending knob. (I would even do this with a "real" Strat if I ever bought one, too. It's that bad for me.)
Anyway, this made me look at guitar design in a whole new light. While that knob might not be a problem for a lot of people (obviously there are a lot of Fender worshipers around!), for me it eliminated a lot of guitars I might ever consider buying. An awful lot of them have a volume knob right up under the bridge pick up. I basically need my controls behind the saddle, so on my next GAS attack, I got an Epiphone LP style. Although I still prefer the Strat-style neck in some ways, the Epi is way more comfortable at the bridge/saddle and the stupid knobs aren't in the way.
I figured I should impart that observation for you to consider as it was something I never thought of at all until I actually had a couple different styles to play for extended periods. If you have limited funds, you should take everything you can into consideration before committing.
...so ever since then, I always hang on to the buckle.