You can use the same exact notes of a melody and harmony, but get a completely different sound or timbre by changing the pickup! You can also change your effects, or amp settings to try something new. In this lesson I show how just changing from the neck pickup with it's bassy, warm tone, to the bridge pickup with a brighter, more trebly tone can make the parts stand out from each other.

Normally, using the same pickup and tone setup will make the parts blend. But this approach is good for making them slightly distinct from each other.